PRODUCT DETAILS

About Bigan P 15 mg/500 mg Tablet

PIOGLITAZONE+METFORMIN is a combination drug consisting of Pioglitazone (Thiazolidinediones), and Metformin (Biguanides) which are called anti-diabetic drugs & used to lower blood sugar levels in diabetic patients. Type 2 diabetes mellitus used to be known as 'non-insulin-dependent diabetes mellitus (NIDDM)' or 'maturity-onset diabetes'. Type 2 diabetes develops if the body does not produce enough insulin, or where the insulin that your body makes does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance that helps to lower the level of sugar in your blood, especially after meals.

PIOGLITAZONE+METFORMIN is a blood sugar-lowering drug which contains a combination of Pioglitazone belonging to the class of thiazolidinediones & Metformin belonging to the class of biguanides. Pioglitazone decreases blood sugar and reverses the effects of Type II diabetes by activating switches (PPAR) inside cells to take up free glucose from blood and decrease its levels in blood. Metformin on the other hand decreases blood sugar by decreasing its formation and increasing its consumption by cells thereby decreasing high blood sugar levels. PIOGLITAZONE+METFORMIN is used in adults to treat type 2 (non-insulin dependent) diabetes mellitus when treatment with metformin alone is not sufficient.

Uses of Bigan P 15 mg/500 mg Tablet

Type II diabetes (Non insulin-dependent diabetes).

Medicinal Benefits of Bigan P 15 mg/500 mg Tablet

PIOGLITAZONE+METFORMIN lowers blood sugar in type II diabetic patients (Non insulin dependent ) & prevents diseases of the heart, kidneys, eyes & blood vessels in feet, which happens due to persistently high levels of blood sugar in diabetic patients. PIOGLITAZONE+METFORMIN plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing. PIOGLITAZONE+METFORMIN lowers blood sugar due to activation of cell switches (PPAR) to take up free glucose from blood & use it for energy production (Pioglitazones)  & decrease production of glucose inside liver (Metformin) .

Directions for Use

PIOGLITAZONE+METFORMIN should not be used unless prescribed by a doctor. Always take PIOGLITAZONE+METFORMIN exactly as your doctor told you. Your doctor will advise you how often you take your tablets on the basis of your medical condition. Swallow the tablet with a full glass of water.

Side Effects of Bigan P 15 mg/500 mg Tablet

Most of the side effects of PIOGLITAZONE+METFORMIN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some common side effects of PIOGLITAZONE+METFORMIN are swelling of sinuses, gas, difficulty sleeping, joint pain, impotence, blood in urine, reduction in blood count (anemia, numbness, taste disturbance, vomiting & diarrhea). It is not necessary for everyone to experience the above side effects. In case of any discomfort, speak with your doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

PIOGLITAZONE+METFORMIN should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking PIOGLITAZONE+METFORMIN, might develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood that can damage the working of your liver and kidney required for the elimination of excess lactic acid from the blood. Before you start taking PIOGLITAZONE+METFORMIN, tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 level. PIOGLITAZONE+METFORMIN, when used with insulin, may extremely lower the blood sugar level leading to hypoglycemia condition, which can be fatal. In this case, your doctor may adjust the dose by lowering the dose of insulin or PIOGLITAZONE+METFORMIN. Prolonged intake of PIOGLITAZONE+METFORMIN may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you are going to have a diagnostic test with an injection of dye or X-ray contrast agent. The use of PIOGLITAZONE+METFORMIN should be stopped for a short time before having an X-ray procedure.

Drug Interactions

Drug-Drug Interaction:

PIOGLITAZONE+METFORMIN interacts with heart medications like (propranolol), pain killers (aspirin, ibuprofen, and celecoxib), high blood pressure-lowering pills (nifedipine, captopril, enalapril, lisinopril), thyroid hormones (thyroxine), antacid (cimetidine), or certain medicines affecting the nervous system.

Drug-Disease Interaction:

 People affected with heart, liver, kidney diseases (like congestive heart failure and myocardial infarction), vitamin B12 deficiency, and alcoholism should avoid intake of PIOGLITAZONE+METFORMIN.

Safety Advice

ALCOHOL

Not recommended with alcohol as it may result in harmful decrease or increase in levels of blood sugar depends on how much alcohol a patient has consumed.

PREGNANCY

Not recommended in pregnancy. PIOGLITAZONE+METFORMIN treatment should be stopped and replaced with any other alternative drug from other blood sugar-lowering agents on recommendation of a doctor. You must tell your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

BREAST FEEDING

Not recommended in breastfeeding mothers. Do not use PIOGLITAZONE+METFORMIN if you are breastfeeding or are planning to breast-feed as doctor's consultation is required.

DRIVING

Safe to use during driving or operating heavy machinery. This medicine will not affect your ability to drive or use machines but care is to be taken if you experience abnormal vision or anything that affects your ability to drive.

LIVER

PIOGLITAZONE+METFORMIN should be used with caution in patients with liver disease as PIOGLITAZONE+METFORMIN has been found to cause harmful interactions in them. Doctors recommendation is required before taking this drug.

KIDNEY

PIOGLITAZONE+METFORMIN should be taken with caution in patients with kidney disease. In rare cases, serious interaction has been found in kidney patients called lactic acidosis thus doctors consultation is required before taking this drug.